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Solubility enhanced itraconazole Anti-fungal gel formulation


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

All our body organs are not like the brain, heart or the lungs. Something is also there which we wear on the otside. Skin is our largest organ—adults carry some 8 pounds (3.6 kilograms) and 22 square feet (2 square meters) of it. This fleshy covering does a lot more than make us look presentable. Its ability to maintain applied preparation intact for a prolonged time have resulted in its increased use as a route of administration whether for local, regional or systemic effects. Gels are better percutaneously absorbed than cream or ointment bases. Itraconazole is a broad spectrum triazole anti-fungal used to contol the prophylaxis of fungal infections in immunocompromised patients. The major drawback of this drug is that it is practically insoluble in water. Solid dispersions have been widely reported as an effective method for enhancing the solubility and dissolution rate. Hence, in the present research work we have successfully developed solid dispersion incorporated gels of Itraconazole to overcome solubility and thus the bioavailability. This book, therefore be useful to those research scholars who are willing to work on gel based formulations.

Product Specifications
SKU :COC85093
AuthorMohd Abdul Hadi,Avanapu Srinivasa Rao and Jeevan Prakash
Number of Pages124
Publishing Year2013-06-17T00:00:00.000
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00