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Solubility Enhancement of Certain Drugs by Solid Dispersion Technique

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Recent advances in novel drug delivery systems (NDDS) aim to enhance safety and efficacy of drug molecules by formulating a convenient dosage form for administration and to achieve better patient compliance. One such approach was fast dissolving tablets which have gained acceptance and popularity in the recent time. Several pharmaceutical industries prepared fast dissolving tablets by direct compression technique by selecting suitable super disintegrants. Direct compression technique offers important advantages such as increased output, reduced cost, less machinery and improved drug stability compared to wet granulation method.The aim of the work is to enhance the solubility, dissolution rate and oral bioavailability of poorly soluble drugs lovastatin and simvastatin by formulating them as solid dispersions using various techniques with PEG-6000 as a carrier and subsequent preparation of fast dissolving tablets with the prepared solid dispersions using different concentrations of super disintegrants and comparing them with that of the marketed product.

Product Specifications
SKU :COC60492
AuthorVidyadhara Suryadevara,Sasidhar Reddyvalam Lankapalli and Ramu Anne
LanguageEnglish
BindingPaperback
Number of Pages228
Publishing Year26.12.2014
ISBN9783659668340
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-05 00:00:00
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