The book sheds light on the role of isospin degree of freedom in reaction dynamics of heavy-ion collisions via transverse in-plane flow. Role of the nuclear symmetry energy and nucleon-nucleon scattering cross section has been envisaged in detail. The investigations presented in the book revealed that the transverse flow can act as a very promising probe of the nuclear symmetry energy at supra-saturation density region, where the nuclear symmetry energy is highly uncertain. The details of nuclear dynamics involving neutron-rich colliding nuclei has also been presented. In short, this book encompasses gross features about the collision dynamics of transverse flow and its disappearance as well as related phenomena of isospin asymmetric nuclei.