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Study of Meiosis

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Reductional nature of meiosis is responsible to maintain the ploidy in eukaryotes. In sexual reproduction, Meiotic division produces gametes of half ploidy and fertilization restores original chromosome number. In the meiosis sister chromatids are monoorientated which leads to separation of homologous chromosomes. This is followed by separation of sister chromatid in meiosis II because of biorientation of sister chromatids. Comparison of meiosis with mitosis reveals that monoorientation of sister chromatids is the main reason for halving the ploidy. According to the present hypothesis, Monopolin complex, A four subunit complex, directs monopolar attachment of sister chromatids. Present study is done to reveal the nature and function of this complex. Cell cycle arrest mutants were created and verified to maximize the number of cells at particular stage by deleting or shuffling the promoter of a particular gene. Then, Csm1 subunit of monopolin complex was affinity tagged and verified in arrested cells. As future prospects of this work affinity purification of Csm1 can be done. Comparison of protein profiles obtained will help to reveal the functional properties of monopolin complex.

Product Specifications
SKU :COC87119
AuthorHimanshu Gupta
LanguageEnglish
BindingPaperback
Number of Pages68
Publishing Year2013-01-07T00:00:00.000
ISBN9783846537190
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00