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Sustained Release Pellets of Ambroxol Hydrochloride


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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Rs. 4,396

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  • Product Description

This book is related to a study involving development and in vitro evaluation of sustained release pellets of ambroxol hydrochloride prepared by extrusion spheronization followed by fluid bed coating with the commercial aqueous polyvinyl acetate dispersion (Kollicoat SR 30 D); aqueous dispersion of ethyl acrylate and methyl methacrylate (Eudragit NE 30 D) and aqueous dispersion of acrylic and methacrylic acid esters (Eudragit RL 30 D and Eudragit RS 30 D). The release of ambroxol hydrochloride from coated pellets was investigated at different coating level. The release mechanism was explored and explained with zero order, first order, Higuchi equation and Korsmeyer’s equation. The Mean Dissolution Time (MDT) value was calculated for all the formulations to determine the release retarding ability of the polymers. The results generated in this study showed that the profile and kinetics of drug release were functions of polymer type, polymer load and physico-chemical nature of the drug. This book will be helpful for the students and researchers of pharmacy discipline specially those who are engaged or interested in research related to modified release pellets dosage forms.

Product Specifications
SKU :COC31145
AuthorIshtiaq Ahmed and Shahana Sharmin
Number of Pages148
Publishing Year8/16/2012
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00