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Synthesis and Antibactarial Evaluation Novel Triazol Derivatives


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  • Product Description

Heterocycles bearing a triazole ring residue are reported to show anticancer, anti-inflammatory, analgesic, antifungal, antitubercular, antimicrobial, antiviral, antioxidant, CNS depressant, and plant growth regulatory activity etc. Keeping in view the importance of Triazole from the literature survey I found various triazole derivatives & from that I planned to work the substituted triazole derivatives from m-nitro benzoic acid, which gives various anticipated biological activities. Among the all synthesized compound, compound 6-(2-chloro-phenyl)-3-(4-nitro-phenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole (PLP 105b) with MIC value of (16µg/ml) against gram-positive (B.subtilis) and (16µg/ml) against gram-negative (E.coli,p.aeroginosa)and the compound3,6-bis-(4-nitro-phenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole (PLP 105d) with MIC value of (16µg/ml) against gram-negative (p.aeroginosa) give better antimicrobial activity than other synthesized compound.

Product Specifications
SKU :COC85044
AuthorChirag J. Patel,Vidyasagar Gali and Patel Pratik
Number of Pages88
Publishing Year2013-04-25T00:00:00.000
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00
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