Synthesis, Docking and QSAR of Isoxazole derivatives

Synthesis, Docking and QSAR of Isoxazole derivatives


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
Delivery in :  10-12 Business Days

₹ 4,165

Availability: Out of stock


Delivery :

5% Cashback on all Orders paid using MobiKwik Wallet T&C

Free Krispy Kreme Voucher on all Orders paid using UltraCash Wallet T&C
Product Out of Stock Subscription

(Notify me when this product is back in stock)

  • Product Description

A series of newer 3-(4'-methoxyphenyl)-5-substituted phenylisoxazoles derivatives have been synthesized by reacting hydroxylamine hydrochloride with chalcone. The chalcones were formed by reacting different aromatic aldehydes with 4-methoxyacetophenone in presence of aqueos KOH. The acute toxicity study was carried on all the synthesized compounds and they were screened for their anti-inflammatory activity by carrageenan induced paw edema method. Anti-inflammatory studies showed statistically significant activity when compared to control indomethacin. The two most potent compounds giving good anti-inflammatory activity were further evaluated for their anti-ulcer activity. The compounds were subjected to docking and quantitative structure activity relationships (QSAR) studies.

Product Specifications
SKU :COC79382
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08
0 Review(s)