Using benzotriazole as auxiliary gives convenient access to a range of 1,2,3,4-tetrahydroisoquinolines with different aromatic substitution patterns. In the light of the well-known difficulties in the preparation of derivatives with electron-withdrawing aromatic substituents and the interesting pharmacological properties of these compounds, the simple procedures and conditions of the described reactions as well as the very high yields, which are frequently obtained, make this approach an important new route to the 1,2,3,4-tetrahydroisoquinoline skeleton.
|Number of Pages||308|
|Country of Manufacture||India|
|Product Brand||LAP LAMBERT Academic Publishing|
|Product Packaging Info||Box|
|In The Box||1 Piece|
|Product First Available On ClickOnCare.com||2015-04-08 00:00:00|