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Tetrahydrobiopterin in ischemia and reperfusion injury


Marketed By :  AV Akademikerverlag   Sold By :  Kamal Books International  
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  • Product Description

The essential co-factor of endothelial nitric oxide synthase (eNOS) tetrahydrobiopterin (BH4) has been repeatedly shown to protect transplanted organs from ischemia reperfusion injury (IRI). So far, the underlying mechanism has not been described. One hypothesis is that BH4 treatment prevents disruption of the functional nitric oxide producing form of eNOS, the so-called "uncoupling" and related superoxide production, by sustaining the dimeric status of the enzyme. Herein we tested this hypothesis in a murine transplantation model.

Product Specifications
SKU :COC76750
AuthorSven-Remmer Hein
Number of Pages88
Publishing Year2014-03-21T00:00:00.000
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandAV Akademikerverlag
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00
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