Call Us 080-41656200 (Mon-Sat: 10AM-8PM)
Free Shipping above Rs. 1499
Cash On Delivery*

The Art of Biochemical Synthesis

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
Delivery in :  10-12 Business Days

 

Check Your Delivery Options

 
Rs. 4,396

Availability: In stock

 
  • Product Description
 

As the most important molecules, proteins often undergo post-translational modifications (PTM) to carry out their functions. In my study, two methods have been developed for the synthesis of proteins containing PTMs. The first method is chemical ligation at valine residue. The thioacid capture ligation was found to be more efficient to overcome steric hindrance of the tertiary thiol group in penicillamine compared with thioester-mediated ligation. The second method is a direct and easy-to-use approach to introducing site-specific acetylation onto recombinant proteins. The free thiol of cysteine was reacted with N-vinylacetamide (NVA) by radical-mediated thiol-ene coupling to generate acetyl-4-thialysine (sLys (Ac)) which is anacetyl-lysine analog. In the last part of this work, we have also introduced a new strategy for selective disulfide formation directed by PNA pairing. This method can be more useful than the DNA-templated reaction systems.

Product Specifications
SKU :COC36281
AuthorFupeng Li
LanguageEnglish
BindingPaperback
Number of Pages152
Publishing Year8/30/2012
ISBN978-3659219689
Edition1 st
Book TypeBiophysics
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00