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The flavin-containing monooxygenase enzyme system


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

In the early phase of preclinical drug development it is important to conduct in vitro/in vivo experiments on the metabolism of new chemical entities in order to predict bioavailability and to clarify metabolic profiles and pathways. This work is fundamental because drug metabolism influences drug efficiency and safety. The flavin-containing monooxygenases (FMOs) is one of the major classes of microsomal monooxygenases responsible for the metabolism of nucleophilic heteratom-containing drugs. This book provides a summary of recent scientific results regarding FMO and provides information about its biochemical, structural and catalytical properties; isoforms; substrate specificity; physiological significance and toxicological importance; relevance in drug metabolism/development; and regulation. The issues discussed in this book should be especially useful for students of the Faculty of Pharmacy and Medicine in order to gain a wider perspective of the field of drug metabolism and for professionals working in the field of Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) science.

Product Specifications
SKU :COC48626
AuthorTímea Borbás
Number of Pages84
Publishing Year2010-05-21T00:00:00.000
Edition1 st
Book TypeBiophysics
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-04-08 00:00:00