Pakistan occupies 6th position in the 22 WHO designated high burden nations. Advocacy Communication and Social Mobilization has been used to address the key challenges faced in the fight against TB. This work guides to support the design and implementation of effective advocacy, communication and social mobilization activities in tuberculosis (TB) control at country level.We concluded in the text of this book that besides the serious security situation in the FATA during whole year the CDR of all the agencies was more than the previous year. It reflects on the importance of ACSM in the awareness of the general population regarding tuberculosis. ACSM strategy in implementing the TB-DOTS is very effective and is now implemented nearly all over the world.It is herby recommended that the ACSM stratagy must also be adopted for the control of other communicable disease as well.