Nowadays, increasing food production to satisfy the increasing food demand of the growing population should be the first task of all nations at any standard. This will be achieved when the sustainability of the agricultural system that directly depends upon plant protection is maintained. Climate change factors such as elevated CO2, high temperature, high or low rainfall and high ozone concentration may alter the current scenario of plant diseases and their management, which certainly have effects on productivity. However, much less is known and investigated on how diseases change under climate change scenario and in turn affect agriculture. Therefore, the analysis of the potential impacts of climate change factors on plant diseases is essential for the implementation of adaptation measures, development of resistant cultivars, new control methods or adapted techniques. This material is helpful for those working on plant diseases, plant disease management, plant stress physiology, food security and anybody interested in the area.