This work is an exploratory research which seeks to find the relationship that exist between senior (top) managers and project managers. The research is done using the phase one of the Carnegie Corporation of New York's Institutional Support Programme to the University of Education, Winneba (UEW) within the period of three years. Chapter one looks at the background of Ghana and the University of Education and a few unavoidable components of a research. Chapter two reviews literature taken cognizance of the Concept of Management, Projects and Programme Management, Leadership, the Role of key players among other issues. Chapter three reviews how Projects and Programmes are managed at UEW, identifying Key players and their roles in implementation and their functional relationship. Chapter four Examines the Carnegie Programme in detail and unearths the key challenges in its implementation. Chapter five is an analysis and discussion session and brings out the issues of the Role of Top Managers, Project Managers, other key players and how all these groups relate. Chapter six summarizes the entire work. The work is suitable for any one in top or down the ladder.