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The Role Of Fibronectin-III1 In The Regulation Of Inflammatory Pathway

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

This book provides potential novel targets for therapies of human cancer and inflammatory diseases. The studies in this book have revealed the cryptic activity within the FnIII-1 module modulates the tissue inflammatory response and suggests that fibronectin (Fn) matrix remodeling can induce the expression of cytokines by stromal cells present in the tissue microenvironment, providing evidence for a previously unrecognized link between fibronectin matrix remodeling and the regulation of the innate immune system. These studies have dissected FnIII-1c's effects on fibronectin matrix from its effects on the activation of intracellular signaling, elucidated the mechanism by which unfolding of fibronectin Type III-1 domain regulates inflammatory response in tissue microenvironment and clarified how local mechanical properties within tissue microenvironment may protect tumor cells from therapeutic treatment.

Product Specifications
SKU :COC97772
AuthorRan You
LanguageEnglish
BindingPaperback
Number of Pages204
Publishing Year2011-09-05T00:00:00.000
ISBN978-3845441948
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-18 00:00:00