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The Role of Onion Extracts in The Prevention of Stroke

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Stroke is the second leading cause of death in the world. Ischemic stroke is characterized by rapid onset of neurological injury due to interruption of blood flow to the brain. Free radicals have been implicated in cerebral ischemia and reperfusion- induced neuronal injury. Hence anti-oxidants have shown neuroprotective effect.The present study investigates the effect of methanolic extracts of a natural anti-oxidant plant - Allium cepa on ischemia and reperfusion induced cerebral injury. Global cerebral ischemia was induced by bilateral carotid artery occlusion for 10 min followed by reperfusion for 24 hr. Cerebral infarct size was estimated using triphenyltetrazolium chloride staining. TBARS assay was employed to measure oxidative stress. Elevated plus maze was employed to evaluate short-term memory. Motor incoordination was evaluated using inclined-beam walking test.Pretreatment with onion extracts reduced cerebral infarct size, attenuated impairment in short term memory and motor coordination along with a decrease in mitochondrial TBARS. Hence, antioxidant plant extracts that attenuate cerebral injury may play an important role in neuroprotection.

Product Specifications
SKU :COC95030
AuthorRicha Shri and Kundan Singh Bora
LanguageEnglish
BindingPaperback
Number of Pages100
Publishing Year2011-02-20T00:00:00.000
ISBN978-3844302363
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-14 00:00:00
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