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The Signal Transduction Pathway - Experimental Drug Design

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

The protein encoded by the ras genes occupies a central position in the signaling pathways used by cells to respond to growth factors. What apparently happens in cancerous tumors is that as a result of mutations in genes, ras proteins are constantly “turned on” so that they constantly promote cell division, even in the absence of stimulation by growth factors. But before either the normal or mutated ras proteins can do anything they have to undergo a series of modifications that enable them to settle in their final home, a spot on the cell membrane from which they relay growth signals to the cell interior. Perhaps by interfering with the modifications of the mutated ras protein, it might be possible to keep the protein from attaching to the membrane – and thus it might be possible to keep the growth turned off and thereby prevent uncontrolled cell division. It is believed that drugs designed on this principle might prove more powerful than conventional chemotherapeutic drugs, which attack all rapidly dividing cells, whether they are cancerous or not.

Product Specifications
SKU :COC29781
AuthorAddai-Mensah Donkor
LanguageEnglish
BindingPaperback
Number of Pages120
Publishing Year1/13/2012
ISBN978-3847345602
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-29 00:00:00