What theoretical molecular biologists must do is to decide propositions or hypotheses. If these propositions or hypotheses are not correct, it must be impossible to get logical theories. Hence, theoretical molecular biologists must pay careful attention to decide the propositions or the hypotheses which really have the solutions. If propositions or hypotheses do not have the solutions, theoretical molecular biologists will not be able to get the solutions from the survey of enormous databases. Therefore, theoretical molecular biologists rely on what they have been experienced and meditated. In other words, theoretical molecular biologist must have their own perspectives on nature. Theoretical scientists should concentrate and think logically to give the solutions to the propositions which they judge to be able to solve, in terms of their own perspectives on nature. What theoretical molecular biologists should do is to search for the fundamental principles which control life phenomena, and logically to prove them.