The toxins has a wonderful characteristics & medicinal values from marine sources which can be handy for researchers working on neuro-degenerative diseases.Neurotoxins are the molecules which block the transmission of the nerve impulse. The marine neurotoxins are widely seen in marine worms, sea anemone, cone snails. Neurotoxins act on nerve terminals and block the transmission of the nerve impulse and are thus most poisonous to the prey and human. Some neurotoxins specifically target ion channels, and different receptors. The structures and the various properties were annotated from PubChem and ChemSpider. The user can retrieve the details of neurotoxin, about its source, structure, its target, and the pharmacokinetics studies. The ADME and toxicology property of the marine neurotoxins was predicted using ADMETOX box. It was found that most of the marine neurotoxins were peptide molecules. It was observed that many marine neurotoxins had the potency to treat various diseases like Alzheimer's, Parkinson's, epilepsy, certain types of cancer and associated pain relief.