Hypertension is a complex, multifactorial, quantitative trait under polygenic control. The fundamental hemodynamic abnormality in hypertension is increased peripheral resistance, due primarily to changes in vascular structure and function. Many of these processes are influenced by trace elements. Small changes in trace elements levels may have significant effects on cardiac excitability and on vascular tone, contractility and reactivity. In studies concerning risk factors for hypertension a number of reports have emphasized the influence of lipids, but the role of dietary minerals other than sodium has been less studied. The present is to screen the trace elements and ultra trace elements in 30 male hypertension patients using ICP ? OES. The level of Al, Ag, Ba, Bi, Cr, Cu, Mg, Mn, Mo, Ni and Se measured in Serum found to be not significantly (P > 0.05) varied when compared to control samples. The serum Zinc and cobalt conc were significantly (P > 0.05) lower in patients with essential hypertension compared to normal subjects and also no correlation between trace elements status with lipid parameters, CRP and hematological parameters.