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Transdermal Drug Delivery System

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

In the recent years, controlled release of drug from the suitable delivery system has attracted academic and industrial researchers and has been coveted approach to improve therapeutic efficacy. Hence, formulation and in vitro evaluation of losartan potassium (LP) loaded transdermal delivery system (TDS) was investigated for controlled release and improved therapeutic efficacy. TDS in the form of patches were prepared by varying the composition of Eudragit RL 100 and Eudragit RS 100. Patches were evaluated for thickness, content uniformity, mechanical properties, moisture uptake and in vitro drug release. Technological parameters for all the formulations were found to be within the limit. In-vitro studies showed relatively low permeation of LP. Inclusion of penetration enhancers (capsaicin & pluronic F-68) resulted increased permeation of LP across human skin. Additionally, study also describes an appropriate animal model for the prediction of human skin permeability. This book provides comprehensive research methodology of TDS & various quality control parameters for the beginners to understand & develop interest in transdermal drug delivery research.

Product Specifications
SKU :COC56042
AuthorKailash C. Petkar and Bhanudas Kuchekar
LanguageEnglish
BindingPaperback
Number of Pages136
Publishing Year2014-07-22T00:00:00.000
ISBN9783659464645
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-06-08 00:00:00
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