The present study provides a detailed analysis of the tropospheric photochemical oxidation processes and ozone photochemical formation under typical polluted urban conditions taking the city of Santiago de Chile as an example. Two field measurement campaigns were carried out in the city of Santiago de Chile during summer and winter. The oxidation capacity of the atmosphere over the urban area of Santiago, Chile and its seasonal dependency has been studied during the two measurement campaigns. The measurement data were used to constrain a simple photostationary-state (PSS) model and a zero dimensional photochemical box model based on the MCMv3.1. Summertime photochemical ozone formation in the urban area of Santiago, Chile has also been investigated using MCMv3.1. The results of the model simulations have been compared with a set of potential empirical indicator relationships. The ozone forming potential of each measured VOC has been determined using the MCM box model. The impacts of the above study on possible summertime ozone control strategies in Santiago are discussed. As a result of this explicit study, questions have been also raised and outlooks to the Future are presented.