Graded levels of crayfish waste meal and poultry offal meal were combined to replace fish meal in the diets of broiler chicken. Performance characteristics, nutrient digestibility, carcass characteristics, serum metabolites and haematology of birds were assessed. The results of the studies indicated that; crayfish wastes that were dried immediately after collection had the highest crude protein content. No significant difference was observed between treatment means in performance and carcass characteristics as well as nutrient digestibility at both the starter and finisher phases. All dietary treatments were similar in performance characteristics at the starter phase. At the finisher phase, chickens fed 75%POM,25%FM showed superiority over others in body weight gain. No significant difference was observed with other parameters monitored.