Starch is a polysaccharide molecule consisting of a large number of glucose monomer units, joined together by glycosidic linkage. ?-amylase is the enzyme, responsible for the breakdown of the glycosidic linkage of starch. Besides the use in starch hydrolysis, ?-amylase enzymes are also used in a number of other industrial applications, such as in laundry and in baking industries. The large scale production of this enzyme has boomed in the last few decades and it is continuously increasing day by day as the demand increases. Every time the researchers look for a new substrate source which is not only cheap but also a comparatively good enzyme producer then the present sources.Considering the above facts, a research work was carried out to look for those source whose market value is almost negligible and enzyme production capacity is appreciable (which may be further improved with certain additives) - wheat bran, jowar bran, sugarcane bagasse powder , potato peel powder and potato dextrose broth (PDB). This work is actually a comparative study of ?-amylase production in the solid state media, with emphasis on utilizing some agricultural wastes having very less commercial values.