Vital parameters for Tilapia Culture in sewage ponds was a research carried out in Ghana as a requirement for an M. Phil certificate from the University of Ghana, to find out the possibility of controlling liquid waste,converting liquid waste into income and quality animal protein. The Background of the study, the problem statement and objectives of the study is recorded in chapter one. Previous studies of the topic was reviewed and recorded in chapter two. Chapter three explained a detail methodology of the study to provide opportunity for those who would like to replicate the study else where in the world. The findings of the study is recorded in chapter four and the discussions of the findings can be seen in chapter five. Some genuine conclusions and recommendations have been suggested in chapter six.