The impact of HIV/AIDS goes beyond individuals infected with the pandemic to reach broadly into the society, both disrupting the functioning of communities and complicating prevention and its treatment. Given the increased quality and length of life of persons living with HIV/AIDS (PLWHA), many organizations are faced with the challenge of accommodating PLWHAs. This study focused on the perceptions of employees towards working with HIV/AIDS infected co-workers at Fedics Food Services in Eastern Cape. The study was done to shade light on the willingness of employees to work with HIV/AIDS colleagues regardless of whether they exist in the organization or not. The study was a quantitative research whereby self administered questionnaires were distributed to respondents. Descriptive data analysis was used to establish employee perceptions on HIV/AIDS and the chi-square was used to determine the levels of significance of each response. The results showed that employees at Fedics Food services were willing to work with HIV/AIDS infected co-workers.