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Wound Healing Properties of some Indigenous Ghanaian Plants


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

The work involves the investigation of 6 indigenous Ghanaian plants P. pinnata, H. opposita, G. arboreum, A. nobilis, F. asperifolia and B. aegyptiaca used for the treatment of bacterial infections and wounds. It also describes the isolation and characterization of the active principles from P. pinnata. Extracts were assessed for in vitro antibacterial activity, usingwild-type and resistant strains of Staph.aureus. P.pinnata, H. opposita, G. arboreum and F. asperifolia showed antibacterial activity. The active compounds in P. pinnata were isolated, using chromatographic techniques and identified with the aid of NMR spectroscopy. The wound healing action of the plant extracts were assessed using in vitro models. P.pinnata, G. arboreum and F. asperifolia at concentrations from 1 to 25µg/ml had a significant stimulatory effect on the proliferation of HDF (142BR) cells. Paullilupeol and paullilupeone isolated from P. pinnata, showed a dose-dependent increase in proliferation of the up to 3µM. All extracts at concentrations 1 to 50µg/ml, had a statistically significant antioxidant protective effect against hydrogen peroxide induced damage to 142BR cells.

Product Specifications
SKU :COC95018
Number of Pages224
Publishing Year2011-01-25T00:00:00.000
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-14 00:00:00